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PARLINFO

 

The Hon. Dr. Kelvin Kenneth Ogilvie

Date of Birth (yyyy-mm-dd):   

Place of Birth:  Nova Scotia, Canada

Profession | Occupation:  professor, university president, scientist, researcher

Federal Political Experience

Years of Service: 2,994 days (8 years, 2 months, 11 days)

Senate

Senatorial Division Political Affiliation at Nomination Term Appointed on the advice of
Annapolis Valley - Hants Conservative Party of Canada 2009-08-27 - 2017-11-06 Stephen Harper

Parliamentary Group

Party Term
Conservative Party of Canada 2009-08-27 - 2017-11-06
Committees - Senate

Committee membership is shown below by session. All members who served on a committee at any time during a session are listed.

Committee Role Term
Standing Committee on Rules, Procedures and the Rights of Parliament Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on National Finance Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Social Affairs, Science and Technology Chair 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Social Affairs, Science and Technology Chair 41st Parliament, 1st Session
(2011-06-09 - 2013-09-13)
Standing Committee on Social Affairs, Science and Technology Chair 41st Parliament, 2nd Session
(2013-10-24 - 2015-08-02)
Standing Committee on Social Affairs, Science and Technology Vice-Chair 40th Parliament, 3rd Session
(2010-03-04 - 2011-03-26)
Standing Committee on Social Affairs, Science and Technology Member 40th Parliament, 2nd Session
(2009-09-29 - 2009-12-30)
Standing Committee on Aboriginal Peoples Member 40th Parliament, 3rd Session
(2010-03-17 - 2010-04-29)
Standing Committee on Agriculture and Forestry Member 40th Parliament, 3rd Session
(2010-03-04 - 2011-03-26)
Standing Committee on Banking, Trade and Commerce Member 40th Parliament, 3rd Session
(2010-11-18 - 2010-11-19)
Standing Committee on Energy, the Environment and Natural Resources Member 40th Parliament, 3rd Session
(2010-04-26 - 2010-04-28)
Standing Committee on Legal and Constitutional Affairs Member 40th Parliament, 3rd Session
(2010-06-23 - 2010-06-23)
Standing Committee on National Finance Member 40th Parliament, 3rd Session
(2010-03-22 - 2010-03-23)
Standing Committee on Transport and Communications Member 40th Parliament, 3rd Session
(2010-10-27 - 2010-10-28)
Standing Committee on Rules, Procedures and the Rights of Parliament Member 40th Parliament, 3rd Session
(2010-03-04 - 2011-03-26)
Standing Committee on Agriculture and Forestry Member 41st Parliament, 1st Session
(2012-02-15 - 2012-02-16)
Standing Committee on Energy, the Environment and Natural Resources Member 41st Parliament, 1st Session
(2013-02-27 - 2013-03-04)
Standing Committee on Legal and Constitutional Affairs Member 41st Parliament, 1st Session
(2013-03-25 - 2013-03-27)
Standing Committee on National Finance Member 41st Parliament, 1st Session
(2013-02-26 - 2013-02-27)
Standing Committee on Agriculture and Forestry Member 41st Parliament, 2nd Session
(2013-10-24 - 2015-02-17)
Standing Committee on Agriculture and Forestry Member 41st Parliament, 2nd Session
(2015-02-18 - 2015-08-02)
Standing Committee on National Finance Member 41st Parliament, 2nd Session
(2015-05-27 - 2015-05-28)
Standing Committee on National Finance Member 41st Parliament, 2nd Session
(2015-03-24 - 2015-03-26)
Standing Committee on Social Affairs, Science and Technology Member 41st Parliament, 2nd Session
(2013-10-24 - 2015-08-02)
Standing Committee on Social Affairs, Science and Technology Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Agriculture and Forestry Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Human Rights Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Committees - Joint

Committee membership is shown below by session. All members who served on a committee at any time during a session are listed.

Committee Role Term
Standing Joint Committee on Scrutiny of Regulations Member 40th Parliament, 2nd Session
(2009-09-29 - 2009-12-30)
Special Joint Committee on Physician-Assisted Dying Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)

Selected Publications

The following is a select bibliography, representing key titles or contributions from the parliamentarian’s collection of published works. To learn more about this parliamentarian’s written works please consult a library near you.

Every effort has been made to ensure the accuracy of the following information. Should you find any errors please contact us via e-mail at: parlinfo@parl.gc.ca.

Isomerization of tert-butyldimethylsilyl protecting groups in ribonucleosides. Carbohydrate Research. 89 (2):203-10 Mar. 2, 1981

Ribonucleotide analogues having novel internucleotide linkages. Tetrahedron Letters. 21 (43):4149-52 1980

Photoreaction of O2,2'-anhydrouridine with ethanol.. Journal of Photochemistry and Photobiology. A, Chemistry. 24 (1):81-2 July 1976

Mass spectra of sterically crowded trialkylsilyl derivatives of nucleosides. Organic Mass Spectrometry. 15 (4):207-19 Apr. 1980

Automated solid phase synthesis of oligoribonucleotides. The synthesis of a tRNA anticodon loop from nucleoside-3'-chlorophosphite derivatives. Nucleosides, Nucleotides and Nucleic Acids. 3 (5):485-98 1984

N-substituted acyclopurinenucleosides with antiviral activity. Nucleosides, Nucleotides and Nucleic Acids. 4 (4):507-13 1985

Ring open analogues of deoxynucleotides. Tetrahedron Letters. 21 (4):327-30 1980

p-Hydroxybenzoylformic acid and (R)-(-)-p-hydroxymandelic acid, two antifungal compounds isolated from the liquid culture of the ectomycorrhizal fungus Pisolithus arhizus.. Canadian Journal of Microbiology. 37(4):258-64 Apr. 1991

Synthesis of 5-substituted-1-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]cytosines. Nucleosides, Nucleotides and Nucleic Acids. 2 (2):147-54 1983

A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2. Antimicrobial Agents and Chemotherapy. 22 (1):55-61 July 1982

Conformational properties of branched RNA fragments in aqueous solution. Biochemistry. 27 (17):6403–16 Aug. 23, 1988

The alkylation of purines, pyrimidines and nucleotides by dialkyl sulfates with tetrabutylammonium fluoride. Tetrahedron Letters. 19 (35):3203-6 1978

Synthesis of novel antiviral compounds. Preparation and rearrangement of 6-methoxyglyceropurines. Canadian Journal of Chemistry. 62:2702-06 1984

Proton magnetic resonance studies of 2'-deoxynucleosides and nucleotides in the syn conformation. Canadian Journal of Chemistry. 56:1170-6 May 1 , 1978

Synthesis of 8,3'-thioanhydroguanosine. Canadian Journal of Chemistry. 50:3276-9 Oct. 15, 1972

Oligoribonucleotide synthesis. The silyl-phosphoramidite method. Methods in Molecular Biology. 20:81-114 1993

Secondary ion mass spectrometry of protected oligonucleotides. International Journal of Mass Spectrometry and Ion Physics. 46:475-8 1983

Synthesis and properties of symmetrically linked diribonucleotides. Nucleosides and Nucleotides. 4:257-8 1985

A complete procedure for the chemical synthesis of oligoribonucleotides. Nucleic Acids Symposium Series. (7):147-50 1980

Experimental ocular herpetic infections in rabbits. Treatment with 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine. A.M.A. Archives of Ophthalmology. 102 (5):778-81 May 1984

2',3'-Carbonates of 8-hydroxypurine nucleosides. Journal of Organic Chemistry. 36 (17):2556–8 Aug. 1971

Synthesis of oligoribonucleotides. Journal of the American Chemical Society. 99 (23):7741–3 Nov. 1977

Simultaneous analysis of nucleosides and nucleotides by high-performance liquid chromatography. Journal of Chromatography A. 205 (1):202-5 Jan. 23, 1981

Attempted cyclization of - (o-Hydroxyphenyl) -butyric acid and other studies. Thesis (B. Sc. (Hons.) )--Acadia University; iii, 33 leaves [1964]

Fluoride ion promoted deprotection and transesterification in nucleotide triesters. Nucleic Acids Research. 7 (3):805-23 Oct. 10, 1979

A general method for selective silylation of primary hydroxyl groups in carbohydrates and related compounds. Carbohydrate Research. 115:234-9 Apr.16, 1983

Antimyocarditic activity of the guanine derivative BIOLF-70 in a coxsackievirus B3 murine model. Antimicrobial Agents and Chemotherapy. 27 (2):184-91 Feb. 1985

Conversion of cytidine into 1-ß--arabinofuranosylcytosine. Carbohydrate Research. 24 (1):210-11 Sept. 1972

Preparation of glyceronucleoside phosphoramidite synthons and their use in the solid phase synthesis of acyclic oligonucleotides. Tetrahedron Letters. 29 (38):4831-4 1988

Derivatization of controlled pore glass beads for solid phase oligonucleotide synthesis. Biotechniques. 6 (8):768-75 Sept. 1988

Uracil analogues of the acyclonucleoside 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]- methyl]guanine (BIOLF-62). Canadian Journal of Chemistry. 62:16-21 Jan. 1, 1984

Synthesis of oligothymidylates on an insoluble polymer support. Canadian Journal of Chemistry. 50:1211-15 Apr. 15, 1972

The synthesis of phosphite analogues of ribonucleotides. Tetrahedron Letters. 21 (43):4145-8 1980

Synthesis and spectroscopic analysis of branched RNA fragments: messenger RNA splicing intermediates. Journal of Organic Chemistry. 53 (16):3710–22 Aug. 1988

Separation and characterization of isomeric substituted nucleosides by gas chromatography and mass spectrometry. Biological Mass Spectrometry. 1 (1):78-9 Feb. 1974

Nonaqueous oxidation of phosphites to phosphates in nucleotide synthesis. Tetrahedron Letters. 22 (27):2531-2 1981

Conversion of uridine 2',3'-carbonates to anhydrouridines. Canadian Journal of Chemistry. 47:495-7 Feb. 1, 1969

Preparation of 9-ß-D-arabinofuranosylguanine (araG). Nucleosides, Nucleotides and Nucleic Acids. 1 (3):233-7 1982

A facile acylation of sterically hindered hydroxyls and a direct replacement of silyl groups by acyl groups in nucleoside chemistry. Tetrahedron Letters. 18 (20):1690-4 1977

Thermal rearrangement of acyl groups in anhydronucleosides. A convenient synthesis of 5'-O-acetylanhydrouridine. Canadian Journal of Chemistry. 50:2365-70 July 15, 1972

A general transesterification method for the synthesis of mixed trialkyl phosphates. Journal of the American Chemical Society. 99 (4):1277–8 Feb. 1977

Use of the tert-butyldimethylsilyl group for protecting the hydroxyl functions of nucleosides. Tetrahedron Letters. 14 (4):317-19 1973

Selective protection of hydroxyl groups in deoxynucleosides using alkylsilyl reagents.. Tetrahedron Letters. 15 (33):2865-8 1974

Time-of-flight secondary mass spectrometry of branched RNA fragments: messenger RNA splicing intermediates. Nucleosides & Nucleotides. 9:445-6 1990

Injector port reactions in gas chromatography : Sources of error in the quantitative analysis of alkylsilyl derivatives of nucleosides. Journal of Chromatography A. 105 (2):297-307 Feb. 26, 1975

Determination of the absolute stereochemistry of the fungal metabolite (R)-(-)-2-(4'-hydroxyphenyl)-2-hydroxyethanoic acid (pisolithin B). Canadian Journal of Chemistry. 69:772-8 May 1, 1991

Nitrate ion as catalyst for selective silylations of nucleosides. Tetrahedron Letters. 22 (48):4775-8 1981

Proton magnetic resonance studies of dinucleotide conformation in aqueous solution. 2'-deoxythymidylyl-(3',5')-2'-deoxy-3'-thymidylate, d(TpTp). Canadian Journal of Chemistry. 53:2781-90 Sept. 15, 1975

The chemical synthesis of oligoribonucleotides VII. A comparison of condensing agents in the coupling of silybted ribonucleosides. Nucleic Acids Research. 8 (9):2105-15 May 10, 1980

The study and characterization of nucleosides by mass spectrometry - I: The mass spectra of pyrimidine 2,2-anhydronucleosides and their derivatives. Organic Mass Spectrometry. 6 (11): 1243-70 Nov. 1972

Synthesis of antiviral compounds. Preparation and rearrangement of 6-methoxyglyceropurines. Canadian Journal of Chemistry. 62:2702-6 Dec. 1, 1984

Developments in the chemical synthesis of naturally occurring DNA and RNA sequences with normal and unusual linkages. Pure and Applied Chemistry. 59:325-30 1987

Comparison of arabinose and ribose nucleoside conformation in aqueous and dimethylsulfoxide solution. 2',5'-Hydrogen bonding in arabinonucleosides.. Biochimica et Biophysica Acta. 478 (3):261-73 Oct. 4, 1977

The chemical synthesis of oligoribonucleotides. IX. A comparison of protecting groups in the dichloridite procedure. Canadian Journal of Chemistry. 58:2686-93 Dec. 1, 1980

Fluoride ion promoted transesterification in phosphate triesters. Journal of the Chemical Society - Chemical Communications. no. 12:443-4 1976

Novel synthesis of 8,2'- thioanhydropurine nucleosides. Journal of the Chemical Society D: Chemical Comunications. no. 16:890 1971

Molecular conformation of 4-Thiouridine in aqueous solution. Canadian Journal of Chemistry. 49:2449-52 July 15, 1971

Dimer formation in the photolysis of diacetylanhydrouridine in aqueous solution. Tetrahedron Letters. 13 (46):4667-8 1972

Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives. Nucleic Acids Research. 14 (16):6453-70 Aug. 26, 1986

Synthesis of 8,2'-thioanhydroguanosine. Canadian Journal of Chemistry. 50:1100-4 Apr. 1, 1972

The tert-butyldimethylsilyl group as a protecting group in deoxynucleosides. Canadian Journal of Chemistry. 51:3799-807 1973

The alkylsilyl protecting groups : in particular, the t-butyldimethysilyl group in nucleoside and nucleotide chemistry. In : International Round Table on Nucleosides, Nucleotides, and Their Biological Applications (5th : 1982 : Research Triangle Park, N.C.). Nucleosides, nucleotides, and their biological applications : proceedings of the 5th International Round Table, October 20-22, 1982. Waltham, Massachusetts: Academic Press; p.209-256. 1983

Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo[2,3-d]pyrimidine nucleoside analogs. Journal of Medicinal Chemistry. 33 (8):2162–73 Aug. 1990

Characterization of a chemically synthesized RNA having the sequence of the yeast initiator tRNA(Met).. FEBS Letters. 269 (1):60-4 Aug. 20, 1990

Preparation, characterization and reactivity of diastereomeric sulfoxides of 8,2'-S-snhydroadenosine. Nucleosides, Nucleotides and Nucleic Acids. 2 (5):399-418 1983

The rapid chemical synthesis of arabinonucleotides. Tetrahedron Letters. 28 (15):1633-6 1987

The automated chemical synthesis of long oligoribonucleotides using 2'-O-silyl-ribonucleoside-3'-O-phosphoramidites on a controlled pore glass support: the synthesis of a 43-nucleotide sequence similar to the 3'-half molecule of an E. coli formyl-methionine tRNA. Journal of the American Chemical Society. 109:7845-54 1987

Gas chromatographic retention data for silyl and acyl derivatives of nucleosides. Journal of Chromatography A. 196 (3):367-78 Aug. 29, 1980

Approaches towards the synthesis of a sulfur analog of ergosterol peroxide. Canadian Journal of Chemistry. 70:158-64 Jan. 1, 1992

Proton magnetic resonance studies of 2'-deoxythymidine, its 3'- and 5'-monophosphates and 2'-deoxythymidylyl-(3', 5')-2' -deoxythymidine in aqueous solution. Canadian Journal of Chemistry. 52:3353-66 Oct. 1, 1974

Time-of-flight secondary ion mass spectrometry of protected isomeric oligonucleotides. Advances in Mass Spectrometry. 11:1402-3 1989

Synthesis of novel isocytosine pseudonucleotide analogues. Nucleosides, Nucleotides and Nucleic Acids. 8 (1):49-64 1989

FT-IR and Raman microprobe spectra of some silylated ribonucleosides. J. Raman Spectroscopy. 20:391-8 1989

Nucleotide chemistry. XV. Developments in syntheses of oligodeoxyribonucleotides and their organic derivatives. Journal of the American Chemical Society. 91 (12):3360–5 June 1969

The study and characterization of nucleosides by mass spectrometry - II: Comparisons between the mass spectra of 3,5-substituted, isomeric pairs of 2,2-anhydrouridines. Organic Mass Spectrometry. 7 (3): 317-25 Mar. 1973

Silica gel as solid support in the synthesis of oligoribonucleotides. Tetrahedron Letters. 21 (43):4159-62 1980

A study on the alkylsilyl groups in oligoribonucleotide synthesis. Journal of Organic Chemistry. 55 (15):4717–24 July 1990

Fluoride ion catalyzed alkylation of nucleic acid derivatives using trialkyl phosphates, dialkyl sulfates and alkyl methanesulfonates. Nucleic Acids Research. 6 (6):2261-73 1979

Necessary protection of the O6-position of guanine during the solid phase synthesis of oligonucleotides by the phosphoramidite approach. Tetrahedron Letters. 26 (21):2525-8 1985

Synthesis of purine and pyrimidine trihydroxyacyclonucleosides. Nucleosides, Nucleotides and Nucleic Acids. 3 (5):537-47 1984

Antifungal antibiotics from Pisolithus tinctorius. Phytochemistry. 30 (4):1113-18 1991

Fluoride ion catalyzed alkylation of purines, pyrimidines, nucleosides and nucleotides using alky halides. Nucleic Acids Research. 6 (4):1695-708 Apr.1979

Total chemical synthesis of a 77-nucleotide-long RNA sequence having methionine-acceptance activity.. Proceedings of the National Academy of Sciences of the United States of America. 85 (16):5764-8 Aug. 1988

Synthesis of nucleotides from 8,2'-thioanhydropurine nucleosides. Canadian Journal of Chemistry. 51:2397-405 July 15, 1973

Novel substrate of adenosine deaminase.. Biochemical and Biophysical Research Communications. 45 (2):297-300 Oct. 15, 1971

Modification of guanine bases: reaction of N2-acylated guanine nucleosides with dichloro-(N,N-diisopropylamino)phosphine. Journal of Organic Chemistry. 51 (18):3559–60 Sept. 1986

Mass spectrometry of trialkylsilyl and acyl derivatives of 2-deoxynucleosides. Organic Mass Spectrometry. 16 (3):129-38 Mar. 1981

Phosphoramidate analogues of diribonucleoside monophosphates. Tetrahedron Letters. 21 (43):4153-4 1980

N-levulination of nucleosides. Tetrahedron Letters. 23 (26):2615-18 1982

Facile alkylation of purines, pyrimidines, nucleosides and nucleotides using tetrabutylammonium fluoride. Tetrahedron Letters. 19 (19):1663-6 1978

Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides. Nucleic Acids Research. 13 (18):6447-65 Sept. 25, 1985

Chemical synthesis of branched RNA: novel trinucleoside diphosphates containing vicinal 2'–5' and 3'–5' phosphodiester linkages. Tetrahedron Letters. 26 (40):4839-42 1985

Phytotoxic metabolites of Phomopsisconvolvulus, a host-specific pathogen of field bindweed. Canadian Journal of Chemistry. 70:2276-84 Aug. 1, 1992

Use of p-nitrophenyl chloroformate in blocking hydroxyl groups in nucleosides. Journal of Organic Chemistry. 32 (2):296–300 Feb. 1967

The study and characterization of nucleosides by mass spectrometry. 3. Comparison between the mass spectra of trimethylsilyl derivatives of purine 2'-and 3'-linked anhydro, thioanhydro, and aminoanhydro nucleosides. Journal of Organic Chemistry. 38 (6):1118-23 Mar. 23, 1973

Deaminase activity of commercial spleen phosphodiesterase. Biochemical and biophysical research communications. 30(3):273-7 Feb. 15, 1968

Studies in aqueouss solution; 2'-deoxythymidine and its 3'- and 5'-monophosphates. 2'-deoxythymidylyl-(3'-5')-2'-deoxythymidine and its ultraviolet photoproduct. In: Harry Steenbock Symposium (4th : 1974 : Madison, Wisconsin). Nucleic acid structure and conformation and protein-nucleic acid interactions: proceedings of the 4th Harry Steenbock Symposium, June 16-19, 1974. University of Wiscosin-Madison: Madison, Wisconsin; p. 597-611. 1975

A new method for the analysis of fully protected oligonucleotides by californium-252 plasma desorption mass spectrometry. 3. Positive ions. Journal of the American Chemical Society. 104 (4):981-4 Feb. 1982

Dimer formation in the photolysis of diacetylanhydrouridine in aqueous solution. Photochemistry and Photobiology. 17 (5):343-5 May 1973

A trihydroxy acyclonucleoside series. Canadian Journal of Chemistry. 62:1622-7 1984

Automated synthesis of gene fragments. Science. 214:270-4 Oct. 16, 1981

Automated oligoribonucleotide synthesis on silica gel supports. Tetrahedron Letters. 25 (7):713-16 1984

The synthesis and functional evaluation of RNA and DNA polymers having the sequence of Escherichia coli tRNA(fMet).. European Journal of Biochemistry. 186 (1-2):87-93 Dec. 8, 1989

Affect of spleen and snake venom phosphodiesterases on nucleotides containing nucleosides in the syn conformation. Biochemical and Biophysical Research Communications. 68 (2):375-8 Jan. 26, 1976

The synthesis of oligoribonucleotides. III. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VIII. Canadian Journal of Chemistry. 57:2230-8 Sept. 1, 1979

N-Phenoxyacetylated guanosine and adenosine phosphoramidites in the solid phase synthesis of oligoribonucleotides: Synthesis of a ribozyme sequence. Tetrahedron Letters. 29 (34):4249-52 1988

Solution and solid phase chemical synthesis of arabinonucleotides. Canadian Journal of Chemistry. 67:831-9 May 1 , 1989

Alkylsilyl groups in nucleoside and nucleotide chemistry. Journal of carbohydrates, nucleosides, nucleotides. 3:197-227 1976

Secondary ion mass spectrometry of protected diribonucleoside monophosphates with a time-of-flight mass spectrometer. Analytical Chemistry. 54 (6):960–6 May 1982

Differentiation between protected diastereomeric trinucleotides by time-of-flight secondary ion mass spectrometry. Organic Mass Spectrometry. 23 (3):228-30 Mar. 1988

A general synthesis of 8,2'-Thioanhydropurine nucleosides. Canadian Journal of Chemistry. 50:2249-53 July 15, 1972

Oligonucleotide syntheses utilizing .beta.-benzoylpropionyl, a blocking group with a trigger for selective cleavage. Journal of the American Chemical Society. 89 (26):7146–7 Dec. 1967

The synthesis of 2'–5' linked oligoribonucleotides. Tetrahedron Letters. 20 (23):2111-14 1979

The preparation of protected arabinonucleosides. Canadian Journal of Chemistry. 61:1204-12 June 1, 1983

Conversion of ribonucleosides to protected 3'-deoxynucleosides. Tetrahedron Letters. 24 (9):865-8 1983

Nucleotide syntheses using O2,2'-anhydrouridine. Canadian Journal of Chemistry. 48:862-4 Mar. 1, 1970

A new method for sequencing fully protected oligonucleotides using californium-252 plasma desorption mass spectrometry. 2. Negative ions of subunits in the stepwise synthesis of a heptaribonucleotide. Journal of the American Chemical Society. 104 (4):976–80 Feb. 1982

Acyclic nucleosides containing two heterocyclic bases. Nucleosides, Nucleotides and Nucleic Acids. 5 (2):169-83 1986

The synthesis of oligoribonucleotides V. The stepwise synthesis of the 3'-terminal heptanucleotide sequence of tRNAfMet from E. coli. Canadian Journal of Chemistry. 57:3140-4 Dec. 1, 1979

Synthesis of a thymidine dinucleotide analogue containing an internucleotide silyl linkage. Tetrahedron Letters. 26:4159-62 1985

Biologically active acyclonucleoside analogues. II. The synthesis of 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62). Canadian Journal of Chemistry. 60:3005-10 Dec. 15, 1982

The use of silyl groups in protecting the hydroxyl functions of ribonucleosides. Tetrahedron Letters. 15 (33):2861-3 1974

Silylated derivatives of arabinonucleosides. Tetrahedron Letters. 23 (19):1997-2000 1982

Study of rearrangement reactions occurring during gas chromatography of tert.-butyldimethylsilyl ether derivatives of uridine. Journal of Chromatography A. 194 (3):379-86 June 27, 1980

Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity. Nature. 344:565-7 Apr. 5, 1990

The synthesis of oligoribonucleotides. II. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VII. Canadian Journal of Chemistry. 56:2768-80 Nov. 1, 1978

Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.. Antimicrobial Agents and Chemotherapy. 22 (6):1026-30 Dec. 1982

The acute toxicity of BIOLF-143 in the rat. Fundamental and Applied Toxicology. 10 (2):313-20 Feb. 1988

Disposition and elimination of BIOLF-143, an antiviral agent, in the rabbit. Fundamental and Applied Toxicology. 14 (1):160-6 1990

Use of isobutyloxycarbonyl as a blocking group in preparation of 3'-O-(p-methoxytrityl)thymidine. Journal of Organic Chemistry. 32 (7):2365–6 July 1967

From public u to private u : an Atlantic Canada opportunity. Halifax, N.S.: Atlantic Institute for Market Studies; vi, 39 p. 2005

Large scale bench-top synthesis of a nineteen unit ribonucleotide on silica gel.. Tetrahedron Letters. 25 (16):1669-72 1984

Prevention of chain cleavage in the chemical synthesis of 2'-silylated oligoribonucleotides. Nucleic Acids Research. 17 (9):3501-17 May 11, 1989

Synthesis of hexanucleotide analogues containing diisopropylsilyl internucleotide linkages. Nucleic Acids Research. 16 (10):4583-94 May 25, 1988

The methyl group as phosphate protecting group in nucleotide syntheses. Tetrahedron Letters. 21 (9):861-4 1980

Oligoribonucleotide synthesis by the phosphite procedure from 2'-dimethoxytritylated nucleosides. Nucleosides, Nucleotides and Nucleic Acids. 4 (1):271-2 1985

A new method for sequencing fully protected oligonucleotides using californium-252 plasma desorption mass spectrometry. 1. Negative ions of dinucleoside monophosphates. Journal of the American Chemical Society. 104 (4):972–5 Feb. 1982

New catalysts and procedures for the dimethoxytritylation and selective silylation of ribonucleosides. Canadian Journal of Chemistry. 60:1106-13 May 1, 1982

Convenient method for stepwise synthesis of oligothymidylate derivatives in large-scale quantities. Journal of the American Chemical Society. 89 (18):4801–3 Aug. 1967

Does the stereochemically controlled elimination of H20 from siliconium ions of nucleosides proceed by oxygen migration?. Advances in mass spectrometry. 8:606-9 1980

Synthesis of 3, N4-dimethylcytidine. Nucleosides, Nucleotides and Nucleic Acids. 2 (4):345-50 1983

Synthesis of nucleotides from O2,2'-cyclouridine. Canadian Journal of Chemistry. 52:1787-97 May 1, 1974

The synthesis of oligoribonucleotides VI. The synthesis of a hexadecamer by a block condensation approach. Canadian Journal of Chemistry. 58:1389-97 July 15, 1980

Synthesis of a purine acyclonucleoside series having pronounced antiviral activity. The glyceropurines. Canadian Journal of Chemistry. 62:241-52 Feb. 1, 1984

Preparation of ribonucleoside 3'-O-phosphoramidites and their application to the automated solid phase synthesis of oligonucleotides. Tetrahedron Letters. 26 (38):4567-70 1985

Nucleotide chemistry. XIII. Synthesis of oligothymidylates via phosphotriester intermediates. Journal of the American Chemical Society. 91 (12):3350–5 June 1969

A proton magnetic resonance study of the ultraviolet photoproduct of d(TpT) in aqueous solution. Canadian Journal of Chemistry. 53:1193-203 Apr. 15, 1975

A facile method for the removal of phosphate protecting groups in nucleotide synthesis. Tetrahedron Letters. 17 (16):1255-6 Apr. 1976

Synthesis of purine, 8, 2'- cyclonucleosides. Journal of Heterocyclic Chemistry. 9:1179-80 1972

Convenient procedure for the preparation of specific mixed DNA-RNA polymers. Journal of the American Chemical Society. 111 (22):8531–3 Oct. 1989

High yield selective 3'-silylation of ribonucleosides. Tetrahedron Letters. 22 (52):5243-6 1981

Sensitivity of equine herpesviruses 1 and 3 in vitro to a new nucleoside analogue, 9-[[2-hydroxy-1-(hydroxymethyl) ethoxy] methyl] guanine. American Journal of Veterinary Research. 44 (6):1032-5 June 1983

9-[[2-Benzyloxy-1-(benzyloxymethyl)ethoxy]methyl]-2-amino-6-chloropurine. Drugs of the Future. 11:826-8 1986

Federal Political Experience

Years of Service: 2,994 days (8 years, 2 months, 11 days)

Senate

Senatorial Division Political Affiliation at Nomination Term Appointed on the advice of
Annapolis Valley - Hants Conservative Party of Canada 2009-08-27 - 2017-11-06 Stephen Harper

Parliamentary Group

Party Term
Conservative Party of Canada 2009-08-27 - 2017-11-06
Committees - Senate

Committee membership is shown below by session. All members who served on a committee at any time during a session are listed.

Committee Role Term
Standing Committee on Rules, Procedures and the Rights of Parliament Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on National Finance Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Social Affairs, Science and Technology Chair 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Social Affairs, Science and Technology Chair 41st Parliament, 1st Session
(2011-06-09 - 2013-09-13)
Standing Committee on Social Affairs, Science and Technology Chair 41st Parliament, 2nd Session
(2013-10-24 - 2015-08-02)
Standing Committee on Social Affairs, Science and Technology Vice-Chair 40th Parliament, 3rd Session
(2010-03-04 - 2011-03-26)
Standing Committee on Social Affairs, Science and Technology Member 40th Parliament, 2nd Session
(2009-09-29 - 2009-12-30)
Standing Committee on Aboriginal Peoples Member 40th Parliament, 3rd Session
(2010-03-17 - 2010-04-29)
Standing Committee on Agriculture and Forestry Member 40th Parliament, 3rd Session
(2010-03-04 - 2011-03-26)
Standing Committee on Banking, Trade and Commerce Member 40th Parliament, 3rd Session
(2010-11-18 - 2010-11-19)
Standing Committee on Energy, the Environment and Natural Resources Member 40th Parliament, 3rd Session
(2010-04-26 - 2010-04-28)
Standing Committee on Legal and Constitutional Affairs Member 40th Parliament, 3rd Session
(2010-06-23 - 2010-06-23)
Standing Committee on National Finance Member 40th Parliament, 3rd Session
(2010-03-22 - 2010-03-23)
Standing Committee on Transport and Communications Member 40th Parliament, 3rd Session
(2010-10-27 - 2010-10-28)
Standing Committee on Rules, Procedures and the Rights of Parliament Member 40th Parliament, 3rd Session
(2010-03-04 - 2011-03-26)
Standing Committee on Agriculture and Forestry Member 41st Parliament, 1st Session
(2012-02-15 - 2012-02-16)
Standing Committee on Energy, the Environment and Natural Resources Member 41st Parliament, 1st Session
(2013-02-27 - 2013-03-04)
Standing Committee on Legal and Constitutional Affairs Member 41st Parliament, 1st Session
(2013-03-25 - 2013-03-27)
Standing Committee on National Finance Member 41st Parliament, 1st Session
(2013-02-26 - 2013-02-27)
Standing Committee on Agriculture and Forestry Member 41st Parliament, 2nd Session
(2013-10-24 - 2015-02-17)
Standing Committee on Agriculture and Forestry Member 41st Parliament, 2nd Session
(2015-02-18 - 2015-08-02)
Standing Committee on National Finance Member 41st Parliament, 2nd Session
(2015-05-27 - 2015-05-28)
Standing Committee on National Finance Member 41st Parliament, 2nd Session
(2015-03-24 - 2015-03-26)
Standing Committee on Social Affairs, Science and Technology Member 41st Parliament, 2nd Session
(2013-10-24 - 2015-08-02)
Standing Committee on Social Affairs, Science and Technology Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Agriculture and Forestry Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Standing Committee on Human Rights Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)
Committees - Joint

Committee membership is shown below by session. All members who served on a committee at any time during a session are listed.

Committee Role Term
Standing Joint Committee on Scrutiny of Regulations Member 40th Parliament, 2nd Session
(2009-09-29 - 2009-12-30)
Special Joint Committee on Physician-Assisted Dying Member 42nd Parliament, 1st Session
(2015-12-03 - 2017-11-06)

Selected Publications

The following is a select bibliography, representing key titles or contributions from the parliamentarian’s collection of published works. To learn more about this parliamentarian’s written works please consult a library near you.

Every effort has been made to ensure the accuracy of the following information. Should you find any errors please contact us via e-mail at: parlinfo@parl.gc.ca.

Isomerization of tert-butyldimethylsilyl protecting groups in ribonucleosides. Carbohydrate Research. 89 (2):203-10 Mar. 2, 1981

Ribonucleotide analogues having novel internucleotide linkages. Tetrahedron Letters. 21 (43):4149-52 1980

Photoreaction of O2,2'-anhydrouridine with ethanol.. Journal of Photochemistry and Photobiology. A, Chemistry. 24 (1):81-2 July 1976

Mass spectra of sterically crowded trialkylsilyl derivatives of nucleosides. Organic Mass Spectrometry. 15 (4):207-19 Apr. 1980

Automated solid phase synthesis of oligoribonucleotides. The synthesis of a tRNA anticodon loop from nucleoside-3'-chlorophosphite derivatives. Nucleosides, Nucleotides and Nucleic Acids. 3 (5):485-98 1984

N-substituted acyclopurinenucleosides with antiviral activity. Nucleosides, Nucleotides and Nucleic Acids. 4 (4):507-13 1985

Ring open analogues of deoxynucleotides. Tetrahedron Letters. 21 (4):327-30 1980

p-Hydroxybenzoylformic acid and (R)-(-)-p-hydroxymandelic acid, two antifungal compounds isolated from the liquid culture of the ectomycorrhizal fungus Pisolithus arhizus.. Canadian Journal of Microbiology. 37(4):258-64 Apr. 1991

Synthesis of 5-substituted-1-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]cytosines. Nucleosides, Nucleotides and Nucleic Acids. 2 (2):147-54 1983

A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2. Antimicrobial Agents and Chemotherapy. 22 (1):55-61 July 1982

Conformational properties of branched RNA fragments in aqueous solution. Biochemistry. 27 (17):6403–16 Aug. 23, 1988

The alkylation of purines, pyrimidines and nucleotides by dialkyl sulfates with tetrabutylammonium fluoride. Tetrahedron Letters. 19 (35):3203-6 1978

Synthesis of novel antiviral compounds. Preparation and rearrangement of 6-methoxyglyceropurines. Canadian Journal of Chemistry. 62:2702-06 1984

Proton magnetic resonance studies of 2'-deoxynucleosides and nucleotides in the syn conformation. Canadian Journal of Chemistry. 56:1170-6 May 1 , 1978

Synthesis of 8,3'-thioanhydroguanosine. Canadian Journal of Chemistry. 50:3276-9 Oct. 15, 1972

Oligoribonucleotide synthesis. The silyl-phosphoramidite method. Methods in Molecular Biology. 20:81-114 1993

Secondary ion mass spectrometry of protected oligonucleotides. International Journal of Mass Spectrometry and Ion Physics. 46:475-8 1983

Synthesis and properties of symmetrically linked diribonucleotides. Nucleosides and Nucleotides. 4:257-8 1985

A complete procedure for the chemical synthesis of oligoribonucleotides. Nucleic Acids Symposium Series. (7):147-50 1980

Experimental ocular herpetic infections in rabbits. Treatment with 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine. A.M.A. Archives of Ophthalmology. 102 (5):778-81 May 1984

2',3'-Carbonates of 8-hydroxypurine nucleosides. Journal of Organic Chemistry. 36 (17):2556–8 Aug. 1971

Synthesis of oligoribonucleotides. Journal of the American Chemical Society. 99 (23):7741–3 Nov. 1977

Simultaneous analysis of nucleosides and nucleotides by high-performance liquid chromatography. Journal of Chromatography A. 205 (1):202-5 Jan. 23, 1981

Attempted cyclization of - (o-Hydroxyphenyl) -butyric acid and other studies. Thesis (B. Sc. (Hons.) )--Acadia University; iii, 33 leaves [1964]

Fluoride ion promoted deprotection and transesterification in nucleotide triesters. Nucleic Acids Research. 7 (3):805-23 Oct. 10, 1979

A general method for selective silylation of primary hydroxyl groups in carbohydrates and related compounds. Carbohydrate Research. 115:234-9 Apr.16, 1983

Antimyocarditic activity of the guanine derivative BIOLF-70 in a coxsackievirus B3 murine model. Antimicrobial Agents and Chemotherapy. 27 (2):184-91 Feb. 1985

Conversion of cytidine into 1-ß--arabinofuranosylcytosine. Carbohydrate Research. 24 (1):210-11 Sept. 1972

Preparation of glyceronucleoside phosphoramidite synthons and their use in the solid phase synthesis of acyclic oligonucleotides. Tetrahedron Letters. 29 (38):4831-4 1988

Derivatization of controlled pore glass beads for solid phase oligonucleotide synthesis. Biotechniques. 6 (8):768-75 Sept. 1988

Uracil analogues of the acyclonucleoside 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]- methyl]guanine (BIOLF-62). Canadian Journal of Chemistry. 62:16-21 Jan. 1, 1984

Synthesis of oligothymidylates on an insoluble polymer support. Canadian Journal of Chemistry. 50:1211-15 Apr. 15, 1972

The synthesis of phosphite analogues of ribonucleotides. Tetrahedron Letters. 21 (43):4145-8 1980

Synthesis and spectroscopic analysis of branched RNA fragments: messenger RNA splicing intermediates. Journal of Organic Chemistry. 53 (16):3710–22 Aug. 1988

Separation and characterization of isomeric substituted nucleosides by gas chromatography and mass spectrometry. Biological Mass Spectrometry. 1 (1):78-9 Feb. 1974

Nonaqueous oxidation of phosphites to phosphates in nucleotide synthesis. Tetrahedron Letters. 22 (27):2531-2 1981

Conversion of uridine 2',3'-carbonates to anhydrouridines. Canadian Journal of Chemistry. 47:495-7 Feb. 1, 1969

Preparation of 9-ß-D-arabinofuranosylguanine (araG). Nucleosides, Nucleotides and Nucleic Acids. 1 (3):233-7 1982

A facile acylation of sterically hindered hydroxyls and a direct replacement of silyl groups by acyl groups in nucleoside chemistry. Tetrahedron Letters. 18 (20):1690-4 1977

Thermal rearrangement of acyl groups in anhydronucleosides. A convenient synthesis of 5'-O-acetylanhydrouridine. Canadian Journal of Chemistry. 50:2365-70 July 15, 1972

A general transesterification method for the synthesis of mixed trialkyl phosphates. Journal of the American Chemical Society. 99 (4):1277–8 Feb. 1977

Use of the tert-butyldimethylsilyl group for protecting the hydroxyl functions of nucleosides. Tetrahedron Letters. 14 (4):317-19 1973

Selective protection of hydroxyl groups in deoxynucleosides using alkylsilyl reagents.. Tetrahedron Letters. 15 (33):2865-8 1974

Time-of-flight secondary mass spectrometry of branched RNA fragments: messenger RNA splicing intermediates. Nucleosides & Nucleotides. 9:445-6 1990

Injector port reactions in gas chromatography : Sources of error in the quantitative analysis of alkylsilyl derivatives of nucleosides. Journal of Chromatography A. 105 (2):297-307 Feb. 26, 1975

Determination of the absolute stereochemistry of the fungal metabolite (R)-(-)-2-(4'-hydroxyphenyl)-2-hydroxyethanoic acid (pisolithin B). Canadian Journal of Chemistry. 69:772-8 May 1, 1991

Nitrate ion as catalyst for selective silylations of nucleosides. Tetrahedron Letters. 22 (48):4775-8 1981

Proton magnetic resonance studies of dinucleotide conformation in aqueous solution. 2'-deoxythymidylyl-(3',5')-2'-deoxy-3'-thymidylate, d(TpTp). Canadian Journal of Chemistry. 53:2781-90 Sept. 15, 1975

The chemical synthesis of oligoribonucleotides VII. A comparison of condensing agents in the coupling of silybted ribonucleosides. Nucleic Acids Research. 8 (9):2105-15 May 10, 1980

The study and characterization of nucleosides by mass spectrometry - I: The mass spectra of pyrimidine 2,2-anhydronucleosides and their derivatives. Organic Mass Spectrometry. 6 (11): 1243-70 Nov. 1972

Synthesis of antiviral compounds. Preparation and rearrangement of 6-methoxyglyceropurines. Canadian Journal of Chemistry. 62:2702-6 Dec. 1, 1984

Developments in the chemical synthesis of naturally occurring DNA and RNA sequences with normal and unusual linkages. Pure and Applied Chemistry. 59:325-30 1987

Comparison of arabinose and ribose nucleoside conformation in aqueous and dimethylsulfoxide solution. 2',5'-Hydrogen bonding in arabinonucleosides.. Biochimica et Biophysica Acta. 478 (3):261-73 Oct. 4, 1977

The chemical synthesis of oligoribonucleotides. IX. A comparison of protecting groups in the dichloridite procedure. Canadian Journal of Chemistry. 58:2686-93 Dec. 1, 1980

Fluoride ion promoted transesterification in phosphate triesters. Journal of the Chemical Society - Chemical Communications. no. 12:443-4 1976

Novel synthesis of 8,2'- thioanhydropurine nucleosides. Journal of the Chemical Society D: Chemical Comunications. no. 16:890 1971

Molecular conformation of 4-Thiouridine in aqueous solution. Canadian Journal of Chemistry. 49:2449-52 July 15, 1971

Dimer formation in the photolysis of diacetylanhydrouridine in aqueous solution. Tetrahedron Letters. 13 (46):4667-8 1972

Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives. Nucleic Acids Research. 14 (16):6453-70 Aug. 26, 1986

Synthesis of 8,2'-thioanhydroguanosine. Canadian Journal of Chemistry. 50:1100-4 Apr. 1, 1972

The tert-butyldimethylsilyl group as a protecting group in deoxynucleosides. Canadian Journal of Chemistry. 51:3799-807 1973

The alkylsilyl protecting groups : in particular, the t-butyldimethysilyl group in nucleoside and nucleotide chemistry. In : International Round Table on Nucleosides, Nucleotides, and Their Biological Applications (5th : 1982 : Research Triangle Park, N.C.). Nucleosides, nucleotides, and their biological applications : proceedings of the 5th International Round Table, October 20-22, 1982. Waltham, Massachusetts: Academic Press; p.209-256. 1983

Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo[2,3-d]pyrimidine nucleoside analogs. Journal of Medicinal Chemistry. 33 (8):2162–73 Aug. 1990

Characterization of a chemically synthesized RNA having the sequence of the yeast initiator tRNA(Met).. FEBS Letters. 269 (1):60-4 Aug. 20, 1990

Preparation, characterization and reactivity of diastereomeric sulfoxides of 8,2'-S-snhydroadenosine. Nucleosides, Nucleotides and Nucleic Acids. 2 (5):399-418 1983

The rapid chemical synthesis of arabinonucleotides. Tetrahedron Letters. 28 (15):1633-6 1987

The automated chemical synthesis of long oligoribonucleotides using 2'-O-silyl-ribonucleoside-3'-O-phosphoramidites on a controlled pore glass support: the synthesis of a 43-nucleotide sequence similar to the 3'-half molecule of an E. coli formyl-methionine tRNA. Journal of the American Chemical Society. 109:7845-54 1987

Gas chromatographic retention data for silyl and acyl derivatives of nucleosides. Journal of Chromatography A. 196 (3):367-78 Aug. 29, 1980

Approaches towards the synthesis of a sulfur analog of ergosterol peroxide. Canadian Journal of Chemistry. 70:158-64 Jan. 1, 1992

Proton magnetic resonance studies of 2'-deoxythymidine, its 3'- and 5'-monophosphates and 2'-deoxythymidylyl-(3', 5')-2' -deoxythymidine in aqueous solution. Canadian Journal of Chemistry. 52:3353-66 Oct. 1, 1974

Time-of-flight secondary ion mass spectrometry of protected isomeric oligonucleotides. Advances in Mass Spectrometry. 11:1402-3 1989

Synthesis of novel isocytosine pseudonucleotide analogues. Nucleosides, Nucleotides and Nucleic Acids. 8 (1):49-64 1989

FT-IR and Raman microprobe spectra of some silylated ribonucleosides. J. Raman Spectroscopy. 20:391-8 1989

Nucleotide chemistry. XV. Developments in syntheses of oligodeoxyribonucleotides and their organic derivatives. Journal of the American Chemical Society. 91 (12):3360–5 June 1969

The study and characterization of nucleosides by mass spectrometry - II: Comparisons between the mass spectra of 3,5-substituted, isomeric pairs of 2,2-anhydrouridines. Organic Mass Spectrometry. 7 (3): 317-25 Mar. 1973

Silica gel as solid support in the synthesis of oligoribonucleotides. Tetrahedron Letters. 21 (43):4159-62 1980

A study on the alkylsilyl groups in oligoribonucleotide synthesis. Journal of Organic Chemistry. 55 (15):4717–24 July 1990

Fluoride ion catalyzed alkylation of nucleic acid derivatives using trialkyl phosphates, dialkyl sulfates and alkyl methanesulfonates. Nucleic Acids Research. 6 (6):2261-73 1979

Necessary protection of the O6-position of guanine during the solid phase synthesis of oligonucleotides by the phosphoramidite approach. Tetrahedron Letters. 26 (21):2525-8 1985

Synthesis of purine and pyrimidine trihydroxyacyclonucleosides. Nucleosides, Nucleotides and Nucleic Acids. 3 (5):537-47 1984

Antifungal antibiotics from Pisolithus tinctorius. Phytochemistry. 30 (4):1113-18 1991

Fluoride ion catalyzed alkylation of purines, pyrimidines, nucleosides and nucleotides using alky halides. Nucleic Acids Research. 6 (4):1695-708 Apr.1979

Total chemical synthesis of a 77-nucleotide-long RNA sequence having methionine-acceptance activity.. Proceedings of the National Academy of Sciences of the United States of America. 85 (16):5764-8 Aug. 1988

Synthesis of nucleotides from 8,2'-thioanhydropurine nucleosides. Canadian Journal of Chemistry. 51:2397-405 July 15, 1973

Novel substrate of adenosine deaminase.. Biochemical and Biophysical Research Communications. 45 (2):297-300 Oct. 15, 1971

Modification of guanine bases: reaction of N2-acylated guanine nucleosides with dichloro-(N,N-diisopropylamino)phosphine. Journal of Organic Chemistry. 51 (18):3559–60 Sept. 1986

Mass spectrometry of trialkylsilyl and acyl derivatives of 2-deoxynucleosides. Organic Mass Spectrometry. 16 (3):129-38 Mar. 1981

Phosphoramidate analogues of diribonucleoside monophosphates. Tetrahedron Letters. 21 (43):4153-4 1980

N-levulination of nucleosides. Tetrahedron Letters. 23 (26):2615-18 1982

Facile alkylation of purines, pyrimidines, nucleosides and nucleotides using tetrabutylammonium fluoride. Tetrahedron Letters. 19 (19):1663-6 1978

Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides. Nucleic Acids Research. 13 (18):6447-65 Sept. 25, 1985

Chemical synthesis of branched RNA: novel trinucleoside diphosphates containing vicinal 2'–5' and 3'–5' phosphodiester linkages. Tetrahedron Letters. 26 (40):4839-42 1985

Phytotoxic metabolites of Phomopsisconvolvulus, a host-specific pathogen of field bindweed. Canadian Journal of Chemistry. 70:2276-84 Aug. 1, 1992

Use of p-nitrophenyl chloroformate in blocking hydroxyl groups in nucleosides. Journal of Organic Chemistry. 32 (2):296–300 Feb. 1967

The study and characterization of nucleosides by mass spectrometry. 3. Comparison between the mass spectra of trimethylsilyl derivatives of purine 2'-and 3'-linked anhydro, thioanhydro, and aminoanhydro nucleosides. Journal of Organic Chemistry. 38 (6):1118-23 Mar. 23, 1973

Deaminase activity of commercial spleen phosphodiesterase. Biochemical and biophysical research communications. 30(3):273-7 Feb. 15, 1968

Studies in aqueouss solution; 2'-deoxythymidine and its 3'- and 5'-monophosphates. 2'-deoxythymidylyl-(3'-5')-2'-deoxythymidine and its ultraviolet photoproduct. In: Harry Steenbock Symposium (4th : 1974 : Madison, Wisconsin). Nucleic acid structure and conformation and protein-nucleic acid interactions: proceedings of the 4th Harry Steenbock Symposium, June 16-19, 1974. University of Wiscosin-Madison: Madison, Wisconsin; p. 597-611. 1975

A new method for the analysis of fully protected oligonucleotides by californium-252 plasma desorption mass spectrometry. 3. Positive ions. Journal of the American Chemical Society. 104 (4):981-4 Feb. 1982

Dimer formation in the photolysis of diacetylanhydrouridine in aqueous solution. Photochemistry and Photobiology. 17 (5):343-5 May 1973

A trihydroxy acyclonucleoside series. Canadian Journal of Chemistry. 62:1622-7 1984

Automated synthesis of gene fragments. Science. 214:270-4 Oct. 16, 1981

Automated oligoribonucleotide synthesis on silica gel supports. Tetrahedron Letters. 25 (7):713-16 1984

The synthesis and functional evaluation of RNA and DNA polymers having the sequence of Escherichia coli tRNA(fMet).. European Journal of Biochemistry. 186 (1-2):87-93 Dec. 8, 1989

Affect of spleen and snake venom phosphodiesterases on nucleotides containing nucleosides in the syn conformation. Biochemical and Biophysical Research Communications. 68 (2):375-8 Jan. 26, 1976

The synthesis of oligoribonucleotides. III. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VIII. Canadian Journal of Chemistry. 57:2230-8 Sept. 1, 1979

N-Phenoxyacetylated guanosine and adenosine phosphoramidites in the solid phase synthesis of oligoribonucleotides: Synthesis of a ribozyme sequence. Tetrahedron Letters. 29 (34):4249-52 1988

Solution and solid phase chemical synthesis of arabinonucleotides. Canadian Journal of Chemistry. 67:831-9 May 1 , 1989

Alkylsilyl groups in nucleoside and nucleotide chemistry. Journal of carbohydrates, nucleosides, nucleotides. 3:197-227 1976

Secondary ion mass spectrometry of protected diribonucleoside monophosphates with a time-of-flight mass spectrometer. Analytical Chemistry. 54 (6):960–6 May 1982

Differentiation between protected diastereomeric trinucleotides by time-of-flight secondary ion mass spectrometry. Organic Mass Spectrometry. 23 (3):228-30 Mar. 1988

A general synthesis of 8,2'-Thioanhydropurine nucleosides. Canadian Journal of Chemistry. 50:2249-53 July 15, 1972

Oligonucleotide syntheses utilizing .beta.-benzoylpropionyl, a blocking group with a trigger for selective cleavage. Journal of the American Chemical Society. 89 (26):7146–7 Dec. 1967

The synthesis of 2'–5' linked oligoribonucleotides. Tetrahedron Letters. 20 (23):2111-14 1979

The preparation of protected arabinonucleosides. Canadian Journal of Chemistry. 61:1204-12 June 1, 1983

Conversion of ribonucleosides to protected 3'-deoxynucleosides. Tetrahedron Letters. 24 (9):865-8 1983

Nucleotide syntheses using O2,2'-anhydrouridine. Canadian Journal of Chemistry. 48:862-4 Mar. 1, 1970

A new method for sequencing fully protected oligonucleotides using californium-252 plasma desorption mass spectrometry. 2. Negative ions of subunits in the stepwise synthesis of a heptaribonucleotide. Journal of the American Chemical Society. 104 (4):976–80 Feb. 1982

Acyclic nucleosides containing two heterocyclic bases. Nucleosides, Nucleotides and Nucleic Acids. 5 (2):169-83 1986

The synthesis of oligoribonucleotides V. The stepwise synthesis of the 3'-terminal heptanucleotide sequence of tRNAfMet from E. coli. Canadian Journal of Chemistry. 57:3140-4 Dec. 1, 1979

Synthesis of a thymidine dinucleotide analogue containing an internucleotide silyl linkage. Tetrahedron Letters. 26:4159-62 1985

Biologically active acyclonucleoside analogues. II. The synthesis of 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62). Canadian Journal of Chemistry. 60:3005-10 Dec. 15, 1982

The use of silyl groups in protecting the hydroxyl functions of ribonucleosides. Tetrahedron Letters. 15 (33):2861-3 1974

Silylated derivatives of arabinonucleosides. Tetrahedron Letters. 23 (19):1997-2000 1982

Study of rearrangement reactions occurring during gas chromatography of tert.-butyldimethylsilyl ether derivatives of uridine. Journal of Chromatography A. 194 (3):379-86 June 27, 1980

Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity. Nature. 344:565-7 Apr. 5, 1990

The synthesis of oligoribonucleotides. II. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VII. Canadian Journal of Chemistry. 56:2768-80 Nov. 1, 1978

Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.. Antimicrobial Agents and Chemotherapy. 22 (6):1026-30 Dec. 1982

The acute toxicity of BIOLF-143 in the rat. Fundamental and Applied Toxicology. 10 (2):313-20 Feb. 1988

Disposition and elimination of BIOLF-143, an antiviral agent, in the rabbit. Fundamental and Applied Toxicology. 14 (1):160-6 1990

Use of isobutyloxycarbonyl as a blocking group in preparation of 3'-O-(p-methoxytrityl)thymidine. Journal of Organic Chemistry. 32 (7):2365–6 July 1967

From public u to private u : an Atlantic Canada opportunity. Halifax, N.S.: Atlantic Institute for Market Studies; vi, 39 p. 2005

Large scale bench-top synthesis of a nineteen unit ribonucleotide on silica gel.. Tetrahedron Letters. 25 (16):1669-72 1984

Prevention of chain cleavage in the chemical synthesis of 2'-silylated oligoribonucleotides. Nucleic Acids Research. 17 (9):3501-17 May 11, 1989

Synthesis of hexanucleotide analogues containing diisopropylsilyl internucleotide linkages. Nucleic Acids Research. 16 (10):4583-94 May 25, 1988

The methyl group as phosphate protecting group in nucleotide syntheses. Tetrahedron Letters. 21 (9):861-4 1980

Oligoribonucleotide synthesis by the phosphite procedure from 2'-dimethoxytritylated nucleosides. Nucleosides, Nucleotides and Nucleic Acids. 4 (1):271-2 1985

A new method for sequencing fully protected oligonucleotides using californium-252 plasma desorption mass spectrometry. 1. Negative ions of dinucleoside monophosphates. Journal of the American Chemical Society. 104 (4):972–5 Feb. 1982

New catalysts and procedures for the dimethoxytritylation and selective silylation of ribonucleosides. Canadian Journal of Chemistry. 60:1106-13 May 1, 1982

Convenient method for stepwise synthesis of oligothymidylate derivatives in large-scale quantities. Journal of the American Chemical Society. 89 (18):4801–3 Aug. 1967

Does the stereochemically controlled elimination of H20 from siliconium ions of nucleosides proceed by oxygen migration?. Advances in mass spectrometry. 8:606-9 1980

Synthesis of 3, N4-dimethylcytidine. Nucleosides, Nucleotides and Nucleic Acids. 2 (4):345-50 1983

Synthesis of nucleotides from O2,2'-cyclouridine. Canadian Journal of Chemistry. 52:1787-97 May 1, 1974

The synthesis of oligoribonucleotides VI. The synthesis of a hexadecamer by a block condensation approach. Canadian Journal of Chemistry. 58:1389-97 July 15, 1980

Synthesis of a purine acyclonucleoside series having pronounced antiviral activity. The glyceropurines. Canadian Journal of Chemistry. 62:241-52 Feb. 1, 1984

Preparation of ribonucleoside 3'-O-phosphoramidites and their application to the automated solid phase synthesis of oligonucleotides. Tetrahedron Letters. 26 (38):4567-70 1985

Nucleotide chemistry. XIII. Synthesis of oligothymidylates via phosphotriester intermediates. Journal of the American Chemical Society. 91 (12):3350–5 June 1969

A proton magnetic resonance study of the ultraviolet photoproduct of d(TpT) in aqueous solution. Canadian Journal of Chemistry. 53:1193-203 Apr. 15, 1975

A facile method for the removal of phosphate protecting groups in nucleotide synthesis. Tetrahedron Letters. 17 (16):1255-6 Apr. 1976

Synthesis of purine, 8, 2'- cyclonucleosides. Journal of Heterocyclic Chemistry. 9:1179-80 1972

Convenient procedure for the preparation of specific mixed DNA-RNA polymers. Journal of the American Chemical Society. 111 (22):8531–3 Oct. 1989

High yield selective 3'-silylation of ribonucleosides. Tetrahedron Letters. 22 (52):5243-6 1981

Sensitivity of equine herpesviruses 1 and 3 in vitro to a new nucleoside analogue, 9-[[2-hydroxy-1-(hydroxymethyl) ethoxy] methyl] guanine. American Journal of Veterinary Research. 44 (6):1032-5 June 1983

9-[[2-Benzyloxy-1-(benzyloxymethyl)ethoxy]methyl]-2-amino-6-chloropurine. Drugs of the Future. 11:826-8 1986